17O in the form of gas and water for Magnetic Resonance Imaging (MRI) and Scientific Applications
Nuclear magnetic resonance (NMR) technology is accelerating a revolution in medical imaging.
NMR technology based on Oxygen-17 uses the magnetic properties of atomic nuclei that occur naturally in the body. Oxygen-17 (17O) is now being used for diagnostic applications and medical research to create a new generation of NMR Images.
New developments with 17O enhance the quality of information about living tissue to improve the practice of medicine in the fields of cardiology and neurology among others.
The magnetic property of 17O makes it to a promising tool for assessing in vivo metabolic tissue information at high fields (≥3T).
Our Oxygen-17 products are manufactured in accordance with cGMP regulations and with the requirements of 21 Code of Federal Regulations: PARTS 210 and 211
We also have Oxygen-17 labeled D-Glucose available (6-O-17-Glucose, ≈ 38at% enriched at position 6). Please contact us for further information.
Specification
Oxygen-17 in the form of water
Physical and Chemical Properties:
| Material | 17O – Oxygen-17 in the form of water with different enrichments |
| Enrichment (available vial size) |
17O ≥ 10 at% (25 g, 50 g) 17O ≥ 20 at% (10 g, 25 g, 50 g) 17O ≥ 40 at% (10 g) 17O ≥ 50 at% (5 g, 10 g) 17O ≥ 60 at% (5 g, 10 g) 17O ≥ 70 at% (1 g, 5 g, 50 g) 17O ≥ 90 at% (1 g, 5 g, 50 g) |
| Purity | ≥ 99,9 % |
| pH | 6 – 8 |
Impurities in μg/g
The following chemical impurities are only valid for 10% and 20% enriched O-17 water. The chemical impurities for the other enrichments are not yet specified.
| Al | ≤ 0,05 |
| Br | ≤ 0,5 |
| Ca | ≤ 0,1 |
| Cl | ≤ 0,5 |
| Co, Cr, Cu | ≤ 0,01 |
| F | ≤ 0,05 |
| Fe | ≤ 0.01 |
| K | ≤ 0,1 |
| Mg | ≤ 0,05 |
| Mn | ≤ 0,01 |
| Na | ≤ 1 |
| NO2 | ≤ 0.1 |
| NO3 | ≤ 0,05 |
| Si | ≤ 1 |
| SO4 | ≤ 0,1 |
| Pb | ≤ 0,01 |
| PO4 | ≤ 0,05 |
| Zn | ≤ 0,05 |
Oxygen 17 in the form of gas
Our Oxygen-17 enriched gas is available in various volumes and two different cylinders (and valves)
1 liter and 2 liter 17O2 (@ standard conditions):
Filled in stainless seamless steel cylinder with 50ml water volume, equipped with a ¼” NPT valve.
5 liter, 10 liter and 20 liter 17O2 (@ standard conditions):
Filled in aluminium alloy gas cylinder with 400 ml water volume and a CGA 540 valve.
Physical and Chemical Properties:
| Material | 17O – Oxygen-17 in form of gas |
| Enrichment | 17O ≥ 70 at% |
| Purity | ≥ 99,9 at% |
Impurities in vppm
| CO | ≤ 10 |
| CO2 | ≤ 100 |
| H2 | ≤ 50 |
| N2 | ≤ 500 |